From Social Marketing to Experiential and everything in between. Our work speaks for itself.


With continued success with Amgen Oncology, Substance now also works with Amgen across the globe, including the region of “Amgen Europe”. We help Amgen Europe stand out as an organisation that brings together science and people. 

Following our success with Amgen Oncology, we started working with the “Amgen ICON” regions to grow their Twitter following, increasing their reach and brand awareness among key audience profiles. Amgen ICON refers to 9 countries: Canada, Mexico, Colombia, Argentina, Brazil, Egypt, Saudi Arabia, UAE and Turkey.


To bring the world of SEGA’s Persona 5 Royal to life in order to inform and promote the game's new features. This would give the European media a chance to play the highly acclaimed game, complete with FIGS subtitles for the first time ever in the franchise.


Cinema is back, and nobody does it quite like Curzon. Known for their atmosphere, comfort, cool locations, and above all their unique and varied film programme, our task was to refresh this exciting brand and remind people of their unique offerings.





Unit 406

Metropolitan Wharf

70 Wapping Wall

London E1W 3SS


+44 (0)20 7067 4730

Los Angeles

4500 Park Granada

#204 Calabasas

CA 91302


+1 310 227 9575

Buenos Aires


+54 9 11 6560 0007

Say hello